New SimpleXYZ 2026 release: our motorised microscope control software (SmartScope / Winkoms)
Over the past few weeks we've taken an important step forward with SimpleXYZ, the application that controls the microscope's XYZ stage and camera for image capture in digital pathology. The standout improvement is the new Sample Scan — see it in action in the video:
✅ Low-cost, compatible solution — runs on Windows 10 and 11 (64-bit) and Linux, developed entirely in-house at Winkoms with OpenSource tools, on SmartScope hardware and adaptable to any other motorised system.
✅ Sample Scan integrated with CapEx Snake — locates the tissue on the slide with a fast panoramic scan (4x objective) and, with a single click, sends the selected area to high-resolution capture (10x objective) without switching modules or repeating the scan.
✅ Multi-language interface — Spanish, Catalan and English, selectable from within the application itself.
✅ Background calibration and region detection (ROI) — uneven-illumination correction and manual drawing of areas of interest directly on the generated mosaic.
✅ Laplacian autofocus for CapEx Snake — initial focus is verified and automatically maintained throughout the whole real-time capture, avoiding out-of-focus images.
✅ User-experience polish — coordinates with 3 decimal places, finer exposure/gain controls, and a complete user manual.
Next steps: automated CI, unified Windows/Linux packaging, and consolidation of the capture workflows.
SimpleXYZ App SmartScopeLite
SimpleXYZ SmartScopeLite
Winkoms have developed the motorized solution, software and hardware, of the SmartScopeLite for microscopiomotorizado.com
- Motorized image capture system. It has the capacity for up to 2 sample holders (75x25mm) per sample holder.
- Works with all microscopy techniques (transmitted light, epifluorescence, and materials).
- The system use autofocus algorithms and captures mosaics in arrays of images (3 axes X, Y, Z) without a limit on images.
- The software will generate the panoramic tiles images with a square spiral movement algorithm.
- All tiles can be Stitched easy with Fiji or Microscoft Image Composite Editor.

https://youtu.be/2tFzSpVen14
1GigaPixel Microscope Image Obj 20x/0.4
Mosaic Image Captured with SimpleXYZ Motorized Stage
Processed with Microscoft Image Composite Editor from Array of 17x17x3 total of 867 images
Microscope iScope
Objective 20x/0.4


